WE ARE OPEN AND HAVE TAKEN ALL COVID 19 PRECAUTIONS

Could Dangerous Allergies be Stopped in Their Tracks?

New research by the faculty at the University of Notre Dame may give hope that life threatening allergic reactions could be prevented with the first ever inhibitor, a treatment that would prevent allergic reactions from happening instead of helping the body through the reaction like current treatments and medications do.

“Our allergy inhibition project is innovative and significant because we brought a novel molecular design approach to selectively inhibit mast cell degranulation — the key event in triggering a food allergic response — which has the potential to improve the quality of life for affected patients,” said Basar Bilgicer, assistant professor of chemical and biomolecular engineering at Notre Dame and an investigator in the University’s Advanced Diagnostics & Therapeutics initiative.

The research was published in the medical journal Nature Chemical Biology, and focused on what is known as Type I hypersensitive allergic reactions, which are severe reactions that can lead to anaphylactic shock. A common example would be severe peanut allergies. The body’s mast cells are a type of white blood cell that reacts to the allergen and causes the allergic reaction. The researchers developed a special molecule they call a heterobivalent inhibitor, or HBI, that can out compete allergens in their attempt to attach to mass cell receptors. Basically, they would prevent the allergic reaction from being possible in the first place.

“Unlike current treatments, such as epinephrine, which help a body endure through an allergic reaction, our HBIs, if introduced into the bloodstream, would actually stop further progression of the allergic reaction from taking place,” said Bilgicer.

“We are figuring out the optimum binding sites on the mast cell receptors to attach to, in order to prevent allergens from interacting with them and to prevent the allergic reaction before it even starts in the first place.”

Sources:

http://www.sciencedaily.com/releases/2013/10/131009125955.htm

http://www.nature.com/nchembio/journal/vaop/ncurrent/full/nchembio.1358.html

You Might Also Enjoy...

New Discovery Could Treat Cystic Fibrosis

Cystic Fibrosis is a devastating genetic disorder which is multi-system, affecting the lungs, sinuses, sweat glands and digestive tract. This illness affects over 30,000 people in the United States alone, with over 700 of these people in Georgia.

Sleep Apnea May Increase Women’s Risk of Heart Disease

Sleep apnea is a silent affliction that affects millions of people every year. It often goes undiagnosed, and has been associated with many health problems from tiredness and lack of focus to high blood pressure to diabetes to mental and emotional problems

Help for Hives

You might think that you are the only one that has them, but you’re not. If you have hives, you are one of MANY! Hives (technically called “urticaria”) is a very common skin problem with the most common symptom being itchiness.

Help for Hives

You might think that you are the only one that has them, but you’re not. If you have hives, you are one of MANY! Hives (technically called “urticaria”) is a very common skin problem with the most common symptom being itchiness.